Sedentary individuals exhibit mitochondrial disregulation, including decreased capacity to oxidize glucose, fatty acids, and amino acids.

“there's an aging process where we lose mandal function and there's like a a sedentary um component right where we lose mandal function”

“we looked that there's significant dis regulation at the mondria level everywhere you look in the mondria in sary individuals uh you see a decreased uh capacity to oxidize to burn glucose uh in terms of pyruvic fatty acids amino acids you see a significantly decrease in electron transport chain as well all the complexes”

“same thing we're doing at the fat oxidation level the cpt1 and cpt2 the Transporters of fat uh they're significantly downregulated as well so that means they're not going to be able to transport fat very well which also matches to the fat oxidation itself where we inject uh fatty acids into the mitochondri they don't oxidize it well so they all match as well”

“you see a significantly decrease in electron transport chain as well all the complexes”

“so we looked into the mandria into mandria so we looked at there significant disregulation at the mondria level everywhere you look in the mondria in sary individuals uh you see a decreased uh capacity to oxidize to burn glucose uh in terms of pyic fatty acids amino acids you see a significantly decrease in electron transport chain as well all the complexes”

“and you see also a significantly decreased capacity in the Transporters of different substrates”

“Living a sedentary lifestyle severely impairs your mitochondria—the essential energy-producing structures that fuel metabolic health, physical endurance, and cognitive performance.”