David Sinclair· PhD
A human genetic variant (rs10496731) is associated with increased levels of the NAD breakdown products called 2PY and 4PY, which increase inflammation and levels of vascular cell adhesion molecule 1 (VCAM-1)…
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
A human genetic variant (rs10496731) is associated with increased levels of the NAD breakdown products called 2PY and 4PY, which increase inflammation and levels of vascular cell adhesion molecule 1 (VCAM-1)…
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