The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
But with repeated use, what ends up happening is that even at similar or higher levels of ingestion, so not just one inhalation a minute, but maybe two inhalations a minute or an inhalation every 30 seconds. Now it's level four out of 10 activation of dopamine and then three and then two. And eventually it drops below baseline.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
if the height of those waves and the frequency of those waves is very very large so some of that water which here I'm using as an analogy to dopamine can slosh out of the wave pool and the Baseline drops
the other thing that happens after those big fast increases in dopamine caused by things like cocaine is afterwards when it quickly drops below Baseline it takes a much longer time to get back to the original Baseline than it did prior to using the drug