Andrew Huberman· PhD
leucine stimulates mTOR.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
leucine stimulates mTOR.
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these amino acids bind to receptors that then downstream result in the activation of TOR. MTOR 1. Specifically MTOR complex 1.
I mean it's very clear that mTOR is amino acid driven. In fact, what's today? Friday? Last Thursday, eight days ago, David Sabatini and his group at MIT published a paper in "Science" that identified the amino acid sensor for mTORC1.
Lucine is the critical signal driving robust activation of mtor