David Sinclair· PhD
Sirtuins are NAD-dependent silent INFORMATION regulators that control the epigenome
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Sirtuins are NAD-dependent silent INFORMATION regulators that control the epigenome
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
And since SIRT1 is NAD⁺-dependent, could NAD⁺ boosters treat or prevent depression?
that sirtuins are nad dependent deacetylase