Peter Attia· MD
so the lactate that gets into so you're generating lactate when you basically are pushing your mitochondria inside your muscle cells to a point Beyond they can where they can generate enough energy in the form of ATP adenosine triphosphate then they sort of have to figure out another way like your cell has to figure out another way to get the energy right so this is where glycolysis comes into play so this is happening outside of the mitochondria and I'm sure your listeners have heard all this before but for those that haven't you know the the lactate generation is then from from that you know metabolism of glucose outside of the mitochondria and that's happening when again you reach that threshold of you know basically you're pushing your your your muscle cells hard enough and their mitochondria can't keep up with you know producing enough energy so the lactate itself and this is this I mean these studies date back to like the 70s uh it's been shown that lactate that it gets into circulation and it's used by other organs as a human source for one as a fuel yeah and the Brain being a big one and and this is now you know this has been you know Decades of of research but um Dr George Brooks has you know he was like one of the first to propose this lactate shuttle Theory and he's you know of course provided evidence for him for that as many others have as well where you know during exercise and after exercise the lactate that is generated you know from muscles that gets into circulation is consumed by the brain this has been shown in humans and animal studies of course but it's consumed by the brain and also not only is it consumed uh it's acting as a signaling molecule