Decreased AMP kinase and intracellular ATP, potentially leading to cessation of protein synthesis, is a preliminary finding in rats that requires further validation.

“And so what we think might be happening is, you're consuming protein and you're-- you're increasing muscle protein synthesis, and then at a certain point, it has enough effect on your energy metabolism in your cells that it short-- not short circuits it, but it cuts it off, right? So again, we're the only ones to show that. That I'm aware of. And that was again, in rats. So I always talk about data. Like, there's data I'm willing to bet my toe on, my foot on, my leg on, and my life on. I'd probably barely bet the end of my little toe on that one. I'm not quite sure.”