The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
we've developed a technique called the lactate clamp technique and it's analogous to the glucose clamp technique which some of our uh some of your physician uh listeners will know about that's where you raise the glucose level to a certain uh raise glucose to a certain level and uh then you can study the production versus the disposal so we Infuse lactate up to four molar and others have raised lactate even to higher
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And nobody actually realized this because unless you use isotope tracers like we did, you know, you eat carbohydrate and your blood lactate rises a little bit. But, actually, the production went way up. It just wasn't removed.