Rhonda Patrick· PhD
with the Dand L-lactate, the D-lactate is neurotoxic.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
with the Dand L-lactate, the D-lactate is neurotoxic.
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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So, actually, one of the tests we did early on, we showed saturation kinetics with L-lactate. And D comes in a linear fashion, so it probably comes in simply by diffusion. So, fortunately, it doesn't share the transporter, which is probably why it's not so neurotoxic in vivo.