The endocannabinoid system exhibits both tonic and phasic capabilities, similar to other neuromodulator systems but with unique mechanisms.

“I think it is fascinating that this whole system has both a tonic like a steady release capability and uh a phasic you know so the ability to spike forgive the p p the neuroscientists will know what I'm talking about to spike more activity of the system superimposed on that tonic activity because this is something that you see in the dopamine system this is something that you see in essentially every neuromodulator neurotransmitter system um but it seems that the endocannabinoid system has accomplished this quite a bit differently”