Peter Attia· MD
it's like beta hydroxybutyrate they go through the same transporter monocarboxylate transport of the MCT transporter to get into the brain
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
it's like beta hydroxybutyrate they go through the same transporter monocarboxylate transport of the MCT transporter to get into the brain
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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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Lactate will outcompete it. So, the first studies we did in 1990, where we did isolated sarcolemmal vesicles. So, imagine a muscle that's got a big membrane sheath and you can actually take the sheath off and it'll form vesicles. And then, you can study the uptake of different things in these vesicles. And so that's how I would describe the lactate transporter. So we compared it to glucose and amino acids and to ketones. And so, lactate is preferred to get in, right? It outcompetes because it really fits the transporter configuration better than the other things do.