The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
elevated levels of acetylcholine have been shown over and over again through beautiful work from Mike Merzenich's lab at UCSF and the Kilgard Lab down in Houston, and a number of other labs, including Norm Weinberger's lab at UC Irvine, again and again, to improve or even directly gate neuroplasticity by increasing focus directly.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
some of those ways include supplementing with things like Alpha-GPC, which is a precursor to acetylcholine.
There are also, fortunately, experiments showing that if you pharmacologically increase acetylcholine, that you can enhance the opportunity for neuroplasticity. You still need to do the learning. You still need to attempt to learn something. You still have to make it incremental, but the amount of plasticity is significantly increased when there's acetylcholine released from nucleus basalis.