Andrew Huberman· PhD
there's actually been some really good brain imaging to try and understand how omega-3 fatty acid treatments are actually changing the brains and neural circuits of people with bipolar. And I will put a reference to this. This is a paper that was published in the American Journal Psychiatry. It's entitled, Omega-3 Fatty Acid Treatment and T2 Whole Brain Relaxation Times in Bipolar Disorder. ... basically what this study shows is that the membranes of neurons within the brains of these people with bipolar disorder, showed more fluidity, more ability of things to move in and around the membranes, which we know is an important component of neuroplasticity in bipolar subjects that were treated with omega-3 fatty acids as compared to bipolar subjects that did not receive omega-3 fatty acids. ... So what that says is that omega-3 supplementation, while not the only intervention that one should consider is something to consider and talk about with your doctor and it's operating in powerful ways. It's not just that it's changing, for instance, your gut microbiome, which is powerful, but is indirect to the brain, it does seem to be having direct effects on neurons and neural circuits.