NMN doses of around 400mg/kg in mice can extend lifespan by 10-15%, with a stronger effect observed in females.

“Shin Imai showed that it actually was pretty good at slowing down the effects of aging, but he stopped the experiment because he ran out of NMN. It used to be rare stuff. Now you can buy it. But we took up the challenge and we've been doing these studies for the last few years in my lab. Now, preliminarily, these mice have less frailty. We've reported that out in the scientific community. They seem to be younger, having better activity, better mitochondrial function. They run further. The lifespan looks promising. We've done it once and they do live longer on NMN. The doses are out 400mgs per kg.”