David Sinclair· PhD
In mice, NMN and NR improve physical energy, cognitive function, and immune response.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
In mice, NMN and NR improve physical energy, cognitive function, and immune response.
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NMN increased endurance in 20-22 month old mice but NR didn’t at same dose.
So Matt also has published that, comparing NR and NMN, only NMN worked in his disease model, which was a mitochondrial disease where those animals really need a boost of NAD.
That at the same dose, NMN will increase endurance. And I forget what that dose was. It might've been 200, 250. [Rhonda]: Yeah, 200. [David]: NMN didn't increase... Sorry, NR did not increase endurance, but NMN did.