Peak LPS response from food consumption typically occurs approximately one hour after a meal.

“food is hard on the gut and... It’s a foreign substance, the risk. I mean, thousands of people die every year from eating out in the United States. Yeah, that’s true. But even in addition to that, in addition to the bacteria that can, you know, come along with eating some bad food, is that just that the gut itself, the gut barrier is sort of to some degree, gets compromised with every meal, you’re releasing a little bit of endotoxin in the bloodstream, because your immune system is activated.”

“it seems as though one hour after a meal is when you really get the peak of an lps response from food”

“When we eat a meal, even if it's a healthy meal, we have a transient opening of the epithelial, you know, cells and the and and the junctions that are that are connecting our epithelial cells lining our gut. There's a transient opening of it and then closes. Um, but when you have that opening, guess what comes out? LPS. LPS comes out. And this is kind of part of what's called the postprandial inflammatory response.”