Paul Saladino· MD
a ketogenic diet low in fiber doesn't lead to decreasing mucus levels in the gut the mucous layer does not go away as some have claimed incorrectly based on flawed animal studies
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
a ketogenic diet low in fiber doesn't lead to decreasing mucus levels in the gut the mucous layer does not go away as some have claimed incorrectly based on flawed animal studies
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despite the lack of fermentable carbohydrates the ketogenic diet maintained the gut mucus layer which you can see here in green that's the gut mucus the blue is epithelial cell and so there were no changes in the thickness of the mucus layer you can see here on the right and no significant differences in the expression of the primary mucin protein mc2
the fact that ketogenic diets no fiber diets do not degrade the gut mucus layer
despite the lack of fermentable carbohydrates the ketogenic diet maintained the gut mucus layer which you can see here in green that's the gut mucus the blue is epithelial cell and so there were no changes in the thickness of the mucus layer you can see here on the right and no significant differences in the expression of the primary mucin protein mc2 so this is definitely in contrast to previous studies where they've they've said oh fiber-free diets degrade the gut mucus layer but those were all fiber free very high sugar diets which do deplete the gut mucus layer
a ketogenic diet probably isn't going to be bad for your gut a low fiber ketogenic diet won't be bad for your gut a fiber a diet without fermentable carbohydrates won't degrade your mucus layer