The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
developing various technologies that could elevate blood ketone levels in the millimolar concentrations that would represent you know turn ative fuel for the brain to keep the brain going under conditions of oxidative stress
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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understanding that these ketones can largely replace glucose as the energy source and then they have these signaling properties that are even independent of metabolism that are remarkable
So, ketogenic diet, it will, definitely, your neurons will switch from using glucose to ketones. We think that's good because, essentially, ketones is a more efficient energy source per cell than glucose. And there is actually less free radicals generated in the burning, if you will, burning ketones compared to glucose. And then, the ketones have these signaling functions affecting gene expression that glucose doesn't have.