Long-term ketosis in healthy humans can lead to electrolyte issues, muscle cramps, palpitations, sleep disturbances, and hormonal imbalances.

“the level of the kidney and thus you get long-term ketogenic side effects electrolyte issues manifesting as muscle cramping heart palpitations sleep disturbances and often hormonal disruption as well”

“some have suggested that at the time my problems with a pure carnivore diet may have been due to my over consumption of organs to me this is absurd i know so many people who have not eaten anywhere near the amount of organs that i was eating on my carnivore diet and had similar problems with long-term ketosis electrolyte issues heart palpitations sleep problems hormonal issues etc”

“the problem that we basically invariably run into with humans is that long-term ketosis is not sustainable for us as humans and so is it a tool yes is it the end result is it the end thing i don't think so make sure it's not sustainable i'm pretty sure it's not sustainable why because the kidney needs insulin signaling to maintain electrolytes and what i've seen so often so often is that we run into palpitations we run into cramping we run into sleep disturbance we run into hormonal changes with long-term ketosis it's just the body really struggles to maintain electrolytes without some level of insulin signaling at the at the kidney uh and electrical maintenance”