The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
There's a population of neurons, nerve cells in your gut, that are exquisitely tuned to the chemistry of whatever it is in your gut. And these are neurons called neuropod cells. ... And there, they are paying attention to, meaning they respond to, amino acids, sugars, and fatty acids.
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I think that in due time we are going to realize that they detect just about every single thing that we put on our mouths every day you know uh that they have some either an a specific receptor that is dedicated to it or a combination of receptors to be able to detect um some of these compounds
some are sensing sugar some are sensing temperature some are sensing pH so relative acidity some are sensing amino acids presumably I mean I've heard it said and I believe there's a a researcher down in Australia who's been very bullish on the theory that we are not exclusively but we are predominantly amino acid foraging machines because we need amino acids for all sorts of important biological processes um and these cells are essentially evaluating how how much sugar how much Lucine how much um uh short chain fatty acid how much um you know essential fatty acids of different kinds
not only the chemical compounds but also an area that I think that is going to be fascinating in the future is the mechanical distension plus uh the the adjustment in temperature as the Kim starts to flow from the mouth into the colon
There's a population of neurons, nerve cells in your gut that are exquisitly tuned to the chemistry of whatever it is in your gut. And these are neurons called neuropod cells. They respond to amino acids, sugars, and fatty acids.