Paul Saladino· MD
the intervention group which is the group that had less saturated fat and more omega-6 linoleic acid from safflower oil had higher rates of death than controls in cardiovascular disease all-cause mortality coronary heart disease
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
the intervention group which is the group that had less saturated fat and more omega-6 linoleic acid from safflower oil had higher rates of death than controls in cardiovascular disease all-cause mortality coronary heart disease
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in short this was a five-year trial with over 9 000 patients and it showed that when you give people more linoleic acid Rich vegetable oil their cholesterol goes down but there was a 22 percent higher risk of death for each 30 milligrams per deciliter reduction in serum cholesterol in the covariate adjusted Cox regression models