A high linoleic acid diet increased urinary excretion of an oxidative product and decreased nitric oxide metabolites compared to a diet rich in saturated fatty acids.

“a high linoleic acid diet when there is a saturated fat lead in leads to increased oxidative stress and decreased nitric oxide metabolism leading to essentially endothelial dysfunction and increased oxidative stress”

“urinary excretion of eight iso prostaglandin f2 also known as eight isoprostane increased after the linoleic acid diet this urinary prostaglandin eight iso pgf2 alpha is known to be associated with oxidative stress and increased in uh atheromas and in people that have oxidized ldl and the urinary concentration of nitric oxide metabolites these are the metabolites that are important for vasodilation and healthy endothelial function decreased in the linolenic acid group”