Orange juice and fructose intake did not induce oxidative or inflammatory stress in a study, possibly due to flavonoids.

“the glucose sweden beverage actually did induce oxidative stress and an inflammatory response so what they say here is that there was a significant increase in reactive oxygen species generated by mononuclear cells polynew polymorphonuclear cells and in nf kappa b binding and mononuclear cells over baseline two hours after glucose intake these changes were absent following fructose orange juice or water intake there was significantly lower reactive oxygen species generation and nf kappa b binding following orange juice fructose in water compared with glucose”

“they found that caloric intake in the form of orange juice or fructose fructose does not induce either oxidative or inflammatory stress possibly due to its flavonoids content and might therefore represent a potentially safe energy source”