Paul Saladino· MD
Fructose is a good example of this: when studied in isolation vs in fruit/honey it appears to have different effects.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
Fructose is a good example of this: when studied in isolation vs in fruit/honey it appears to have different effects.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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fructose performs very differently in those matrices of whole foods than it does in isolation
and the studies in humans with fructose are feeding isolated fructose something that never happens in nature you're always eating fructose with glucose or other sugars