A diet rich in omega-6 fatty acids can induce cardiac abnormalities, cellular death, and necrosis in rats, particularly when hyperglycemic.

“this was the one that you were showing the photos of and so if people actually want to read this study this is a brief episode of streptozoacin induced hyperglycemia produces cardiac abnormalities in rats fed a diet rich in n6 pufa as we said in the beginning of the podcast n6 pufa is essentially linoleic acid and omega-6 and you can see that there are many uh there's a lot of evidence of actual cellular death cardiac cell necrosis and problems with cardiac function in these mice when they become hyperglycemic on an excess polyunsaturated n6 diet”