Paul Saladino· MD
what you are seeing in these charts is the marker of linoleic acid breaking down into a toxin in the cell and the cell struggling to reduce it from the cell
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
what you are seeing in these charts is the marker of linoleic acid breaking down into a toxin in the cell and the cell struggling to reduce it from the cell
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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the n6 pufa diet decreases reduce glutathione increases oxidized glutathione at least in the group that was made hyperglycemic and the ratio is very different
here's one more study that looks at a high fat diet in mice inducing changes in adipose tissue and breakdown products of linoleic acid including hne and what do they do they gave mice diets that were higher in linoleic acid and they saw higher levels of hne in certain fatty acid Depots