Paul Saladino· MD
we know that ketones share a common pathway of synthesis with cholesterol as well and that increasing saturated fat in the diet can lead to increased cholesterol synthesis
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
we know that ketones share a common pathway of synthesis with cholesterol as well and that increasing saturated fat in the diet can lead to increased cholesterol synthesis
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I think that the ketone body production the enzymatic machinery that's activated to make ketones is also making cholesterol and that's why LDL is being directly secreted into the circulation
the other thing you said that I want to highlight is that glucose and ketones are made into cholesterol yeah we had spoken about this a little bit on the first podcast you are not surprised when we had talked about increasing levels of LDL reflective of higher levels of total cholesterol in the body on ketogenic diets because of the shared pathway of ketones and cholesterol or ketones being used to make cholesterol in the periphery and in the brain through a CoA and the metal on a pathway yeah and that could be put and that could be and so they should the the beginning of the pathway is is shared