Andrew Huberman· PhD
In general, most people should probably strive to get somewhere between 500 milligrams and a gram of choline per day.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
In general, most people should probably strive to get somewhere between 500 milligrams and a gram of choline per day.
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I said that I'd seen some studies where some people need 1200 milligrams of choline that's the people with the worst MTHFR activity
there are human studies where it has been shown that some people require 1200 milligrams of choline a day and those studies are not looking at liver fat they're looking at other markers but people who have a genetic predisposition to need what we know is the highest