The gut-brain circuit activated by glucose can be targeted to modulate sugar wanting.

“And so we need to come up with strategies that can meaningfully change the activation of these circuits that control our wanting certainly in the populations at risk, and this gut brain circuit that ultimately it's the lines of communication that are informing the brain, the presence of intestinal sugar, in this example, it's a very important target in the way we think about, is there a way that we can meaningfully modulate these circuits?”