Rhonda Patrick· PhD
however 44% of women have a gene polymorphism in the pemt gene which does not allow them to make choline from phosph choline this specific polymorphism does not respond to estrogen which is known to activate the pemt gene
The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
however 44% of women have a gene polymorphism in the pemt gene which does not allow them to make choline from phosph choline this specific polymorphism does not respond to estrogen which is known to activate the pemt gene
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For this reason women with this polymorphism have to increase their dietary intake of choline egg yolk is a great source of choline