Increased linoleic acid in the inner mitochondrial membrane reduces ATP production efficiency by making the membrane leaky.

“it's in that as you said it's in that inner mitochondrial membrane where all these little pieces of the electron transport chain occur and the body as electrons move through that chain at a high level the electrons that come from the food we eat whether it's food from fat whether it's electrons from fat or electrons equivalents from carbohydrates we'll get to that they move through the electron transport chain and as they're doing that the whole point of doing that is to move protons right between those two membranes to create a gradient essentially a battery and this evidence that polyunsaturated fats in those membranes makes that battery leaky is so profound it's like wait you're making a battery to run your life and the linolic acid makes the battery crappy it just makes it leak the the polarity of the battery which is what you need to carry the energy because at the end of the electron transport chain those protons move that gradient you've created moves through this little motor this microscopic motor called atpa and it makes ATP and if there's not as many protons move through that you make less ATP”

“there's Quantum leak of these protons with more linolic acid in these membranes that to me is just freaking profound”

“we know that excess linolic acid accumulates in the mitochondrial membranes it causes proton leak across the interner mitochondrial membrane which loses the at you know which causes less ATP to be made in the electron transport chain”