David Sinclair· PhD
there are certain optimal body weights that, it's clear that if you're carrying excess weight, you're going to accelerate your aging clock.
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The headline is broadly defensible, but the qualifications matter. Effect sizes vary by population, the strongest claims rest on shorter trials, and credible voices push back on how it's typically framed.
there are certain optimal body weights that, it's clear that if you're carrying excess weight, you're going to accelerate your aging clock.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
What we don't want people to do is get the idea though that oh good uh this works even if you're overweight and so I can stay overweight and then as long as I fast a little it's going to be fine. That's that's not what you're saying also