In insulin-resistant obese individuals, impaired mitochondrial function leads to reduced fat burning, increased triglycerides, and difficulty losing weight.

“so the lower inflamed obese were also insulin resistant okay yeah so it didn't crack just with it right instant resistance so insulin resistance is associated with a shift of metabolism that shifts away from what they call fatty acid oxidation by the mitochondria and what that does the net effect of having the lower ability to burn fat is that it's hard to lose weight that's one thing but the other thing that's Associates with poor burning of fat is that things tend your your your blood lipids tend to go up or associate with the increased blood lipids like triglycerides”