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CHORIBar: Micronutrients, Fiber & Polyphenols in a Bar — Whalespan

Content›Video›CHORIBar: Micronutrients, Fi…

CHORIBar: Micronutrients, Fiber & Polyphenols in a Bar

Rhonda Patrick58m · 2015-09-02

Claims Made

96

Claims Supported

79

Support Rate

82%

Support rate

79 of 96 claims supported

79 supported17 partial / not

Claims from this content

70

✓Well SupportedVitamin D influences gene expression by interacting with approximately 20,000-30,000 gene receptors throughout the body.✓Well SupportedRaising HDL particle count may be a more relevant metric for improving reverse cholesterol transport and clinical outcomes than just HDL cholesterol.✓Well SupportedMagnesium can be obtained from leafy green vegetables, kale, spinach, and nuts.✓Well SupportedApoB-containing lipoproteins deliver lipids for growth or repair, and excessive deposition without removal leads to atherosclerosis.Well Supported

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Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.

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✓

Folic acid levels below a certain threshold, affecting 10% of the US population, can lead to chromosome breakage.

✓Well SupportedAt least three specific ingredients in the Quarry bar are necessary to raise HDL levels.

✓Well SupportedThe CHORIBar is designed to fill nutritional gaps in suboptimal diets, potentially improving metabolism.

✓Well SupportedInflammation can transform larger, buoyant LDL particles into small, dense LDL particles.

◐Partially SupportedSoluble fiber provides a viscous barrier that modulates nutrient absorption and is metabolized by gut bacteria into beneficial metabolites that nourish the gut wall.

✓Well SupportedObesity is linked to accelerated onset of major diseases including cancer, cognitive decline, immune dysfunction, and cardiovascular disease.

◐Partially SupportedThe beneficial effects of CHORIBar on metabolic markers are blunted in obese individuals with high chronic inflammation.

◐Partially SupportedSome nutrients facilitate the absorption of other ingredients, while fiber can impede nutrient absorption.

◐Partially SupportedA 2012 study in lean, middle-aged adults showed that a specific bar formulation significantly increased HDL cholesterol, particularly the HDL2b particle subtype.

◐Partially SupportedNourishing the gut wall strengthens it and enhances its ability to power the immune system.

◐Partially SupportedAn early trial of the CHORIBar showed a statistically significant rise in HDL levels.

◐Partially SupportedSupplementing with essential nutrients may help obese individuals who have struggled with traditional dietary changes.

◐Partially SupportedThe body requires approximately 30 different vitamins and minerals, which primarily act as cofactors for enzymes involved in metabolism.

◐Partially SupportedThe CHORIBar is designed to fill nutritional gaps in the Western diet and has scientific support for improving metabolic factors.

◐Partially SupportedMicronutrient deficiencies can cause cumulative damage and age-related diseases over decades.

◐Partially SupportedYounger individuals (under 30) may not require significant reverse cholesterol transport, explaining the lack of HDL increase observed in this age group.

◐Partially SupportedThe default dosage for micronutrients in the Quarry bar is approximately one-quarter of the Recommended Dietary Allowance (RDA) per bar.

◐Partially SupportedObese individuals often consume diets with a poor ratio of essential minerals and vitamins to calories, characterized as 'empty calories'.

✓Well SupportedMitochondrial dysfunction negatively impacts fat metabolism, and imbalanced fatty acids can increase inflammation.

◐Partially SupportedThe Quarry bar improves lipid profiles by increasing HDL and decreasing LDL.

◐Partially SupportedWhole foods work in concert, with each component having a function, similar to a factory requiring all parts for product manufacture.

✕Not SupportedEpidemiological studies in nutrition often yield incorrect answers or associations due to complexity and potential for misinterpretation.

✕Not SupportedStatin side effects can include mitochondrial targeting leading to muscle wasting, and some statins can inhibit cholesterol synthesis in the brain.

◐Partially SupportedThe Quarry bar may lower small dense LDL particles and raise HDL, potentially comparable to statins without lowering total LDL cholesterol.

◐Partially SupportedInsoluble fiber promotes gut motility, which is essential for timely nutrient absorption and waste elimination.

◐Partially SupportedCholesterol is essential for metabolism and survival, and the goal is to tune metabolism for health, not to eliminate all cholesterol.

◐Partially SupportedResearchers are identifying new compounds that improve cellular resiliency to environmental stresses like dietary fat in cell culture models.

◐Partially SupportedSelenium is a required nutrient that can be toxic in both too little and too much amounts, with varying levels found across different regions.

◐Partially SupportedIntravenous infusion of a synthetic HDL version in patients with prior myocardial infarction stripped plaques off arteries and significantly reduced small dense LDL particles.

◐Partially SupportedThe Quarry bar is designed to tune up metabolism and may reduce inflammation.

◐Partially SupportedThe CHORIBar does not appear to increase HDL in individuals under 30 years old.

◐Partially SupportedEarly trials of the CHORIBar were met with significant compliance challenges due to its poor taste.

◐Partially SupportedThe fiber content in the CHORIBar may contribute to satiety and reduce food intake in obese individuals.

◐Partially SupportedMaintaining gut barrier function is crucial to prevent bacteria and food antigens from entering the body.

◐Partially SupportedThe Quarry bar might serve as an adjunct to or replacement for statins.

◐Partially SupportedWhen intake is low, the body prioritizes survival and reproduction vitamins and minerals over those protecting against long-term damage.

✕Not SupportedInsufficient vitamin D levels can negatively affect thousands of genes and disrupt metabolism.

◐Partially SupportedThe CHORIBar is well-suited for societies with diets high in carbohydrates, low in vitamins and minerals, and associated with obesity.

◐Partially SupportedThe Quarry bar is theoretically helpful for obesity-related conditions, with encouraging preliminary results in obese adolescent asthmatics.

◐Partially SupportedA deficiency in zinc can inactivate approximately 2,000 enzymes.

◐Partially SupportedThe CHORIBar may need to be formulated as an anti-inflammatory agent for individuals with high chronic inflammation.

◐Partially SupportedA substance is defined as a vitamin if it is required in the diet for metabolism and if its absence leads to death in a rat.

◐Partially SupportedNutrition may offer a more effective approach than drugs for preventive medicine.

◐Partially SupportedThe Quarry bar may help pre-diabetics prevent the transition to diabetes.

◐Partially SupportedMany people, including wealthy Americans, have vitamin and mineral deficiencies.

◐Partially SupportedThe CHORIBar is a 30-gram bar containing vitamins, minerals, fiber, omega-3 fatty acids, fruit polyphenols, and small molecules for gut health, with no added sugar and low calories.

◐Partially SupportedChronic inflammation can divert resources from metabolic regulation.

◐Partially SupportedPreventing inflammatory triggers from the gut lumen from entering the body can prevent inflammation and abdominal fat deposition.

◐Partially SupportedIn obese individuals, an eight-week intervention showed a decline in inflammation but not a significant rise in HDL or HDL2b.

◐Partially SupportedInadequate intake of vitamins, minerals, and fiber may contribute to metabolic dysfunction associated with obesity.

?Limited ResearchA two-month trial of the CHORIBar showed a decrease in inflammation, but it is unclear if longer duration would yield more significant anti-inflammatory effects.

✕Not SupportedExcess intake of various nutrients can lead to adverse outcomes.

◐Partially SupportedChildren can tolerate higher sugar intake than adults without immediate negative health impacts.

◐Partially SupportedThe Quarry bar may act as a transitional aid for dietary changes by improving how individuals feel.

◐Partially SupportedA balanced diet with 30 different vitamins and minerals is necessary for health.

◐Partially SupportedThe CHORIBar contains ingredients that power mitochondria, enabling sufficient ATP production to maintain the integrity of the GI tract.

◐Partially SupportedFiber is crucial for gut health and cannot be effectively delivered in pill or drink form, necessitating a bar format for delivery.

◐Partially SupportedThe Quarry bar research and development has involved over a dozen clinical trials.

◐Partially SupportedThe CHORIBar combines fiber, micronutrients, vitamins, minerals, polyphenols, and omega-3 fatty acids.

◐Partially SupportedEven individuals eating a healthy diet may benefit from increased intake of micronutrients, fiber, and polyphenols.

◐Partially SupportedA lack of essential vitamins can lead to the inactivation of about a quarter of the body's metabolism.

◐Partially SupportedThe CHORIBar is low in calories (125-130 kcal) and contains no added sugar.

◐Partially SupportedAdvanced analytical methods will soon allow for inexpensive measurement of 1500 human plasma proteins from a fingerprint of blood.

◐Partially SupportedDrugs work by perturbing metabolic processes, whereas a balanced diet promotes healthy function without expected side effects.

◐Partially SupportedAbdominal fat accumulation is a response to the body's attempt to manage gut contents, mediated by increased insulin.

◐Partially SupportedIn insulin-resistant obese individuals, impaired mitochondrial function leads to reduced fat burning, increased triglycerides, and difficulty losing weight.