Andrew Huberman· PhD
Okay, so, first of all, it's regulating more than 5% of the protein-encoded human genome.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Okay, so, first of all, it's regulating more than 5% of the protein-encoded human genome.
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Because, again, it's a hormone. It's regulating more than 5% of your protein-encoding human genome.
because again it's a hormone. It's regulating more than 5% of your protein encoding human genome.
So first of all, it's it's regulating more than 5% of the protein encoded human genome.
you know, getting enough sleep, you know, when you're when you're stressed, when your cortisol goes up, you know, chronically, you're depleting magnesium. you know, it's it's it's it's very like magnesium is being used to deal with that stress, right? So, >> there there's a reason that we need things like magnesium and, you know, vitamin D. It's a it gets converted into steroid hormone changing 5% of our, you know, our our genome.
the important thing about vitamin d is it speaks to our genes it's you know 20 you know 30 000 gene receptors throughout the body and so they're all what listening to how much sunlight vitamin d is around
Vitamin D controls over 1,000 genes.
Vitamin D transcends its role as a mere vitamin; it is a potent steroid hormone that directly interacts with our DNA, orchestrating the activation and suppression of over 5% of the protein-encoding human genome, essentially influencing numerous bodily functions and systems.
regulates over 5% of your genome, including genes for viral defense, neurotransmitter synthesis, and longevity
Vitamin D is a steroid hormone regulating thousands of genes through specialized DNA sequences called Vitamin D response elements.
Vitamin D functions as a steroid hormone and regulates nearly 5% of the human genome, including key genes crucial to immune defense, which explains its powerful role in respiratory health.
vitamin D is actually a steroid hormone that controls the expression of over a thousand different genes in your body what that translates to is vitamin D actually controls over a thousand different physiological processes inside of your body
And the nice thing about these steroid hormones is they bind to a receptor, which goes to the DNA and recognizes 12 bases in the DNA, the 6 bases, 3 base spacer, and then another 6 bases. And what that does is that's the telltale signature of estrogen or vitamin D hormone. So it's a steroid hormone, and it's controlling a thousand genes, lots of them in your brain.
vitamin D gets converted into a steroid hormone a hormone that regulates the expression of over a thousand different genes in your body that's a thousand different physiological processes in your body being regulated by this steroid hormone vitamin D
vitamin D is a steroid hormone just like estrogen and over a thousand genes have a signal on the gene that says that's where vitamin d and vitamin D receptor land and either turn on the gene or turn off the gene
the active steroid hormone and it's it actually regulates the expression of over a thousand different genes in the human body
the first thing to know about vitamin D is that it is not just a vitamin it's a steroid hormone underscoring its importance for health it actually regulates more than five percent of the protein encoding human genome
So, I do think like, you know, thinking about mechanism, and I know, you've talked about, you know, the role looking, you know, underlying mechanisms, how does vitamin D regulate the immune system? I mean, there's a variety of ways.
And, you know, it is a steroid hormone that is doing similar things like testosterone in the sense where is a binding receptor going into the cell nucleus and regulating... Yeah. Like, 5% of the protein encoding human gene a lot.
vitamin D gets converted into a steroid hormone and it goes into the nucleus of cells and interacts with DNA so it recognizes a very specific sequence of DNA called the vitamin D response element and and this is encoded in our DNA um and that interaction then either turns genes on and activates them or it does the opposite it sort of turns them down and represses them so it's very important for orchestrating I mean we're talking about over 5% of the protein encoding human genome is regulated by vitamin D which is quite a lot
Vitamin D gets converted into a steroid hormone that regulates over a thousand genes in our body. It enters the nucleus of our cells and it regulates, it activates and turns on or it suppresses and turns off up to nearly 5% of the protein encoding human genome.
We know that vitamin D controls about 5% of the protein encoding human genome. That's over a thousand genes.