David Sinclair· PhD
Higher omega-3 levels are linked to ~15–20% lower mortality risk.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Higher omega-3 levels are linked to ~15–20% lower mortality risk.
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People that supplemented fish oil or ate fish had an 18% lower all-cause mortality & a 23% decrease in cancer death.
we saw the same thing in all it wasn't as strong in cancer it wasn't as stair-steppy like it was in cardiovascular but the highest group in omega-3s did have a significantly lower risk of death and cancer but it interesting to me is the non-cardiovascular non-cancer all these other causes of death from electrocution to suicide to car accidents to kidney failure you know everything people die of um the higher the omega-3 just like cardiovascular lower risk
in another study we published from framingham just one cohort we did see that there's roughly a five-year difference if you're at the very lowest omega-3 versus the highest your your odds of dying are about five years earlier
so the the general attack of both of our our study and nature communications on total mortality with our 17 cohorts and this latest one in american journal clinical nutrition in framingham point to having a high omega-3 level is protective and in the same sense that having a low cholesterol is protective in the same sense that having low blood pressure is protective it's about the same predictive value
and we found that the people had the highest omega-3 levels compared to the lowest were 15 or so less likely to die over that time and it was a very when you look at quintiles of omega-3 it was very dose dependent the