Andrew Huberman· PhD
They should work because they operate in the very same biochemical pathways that antidepressants that are prescribed to people do.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
They should work because they operate in the very same biochemical pathways that antidepressants that are prescribed to people do.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
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We also talked about exercise and how EPA and exercise on a regular basis can offset these inflammatory pathways.
So you've got multiple steps here. We're describing two tools, increasing EPA and regular exercise as a way of increasing serotonin, somewhat indirectly, right? It's by limiting this bad pathway to promote the activity of a good pathway.
From the data that are published in quality peer review journals, it really appears that this inflammation pathway does function to increase depression through these pathways. And so, knowing that there are behavioral steps and supplementation-based steps, or if you prefer, getting your EPAs from typical food, from nutritional approaches, I find that very reassuring that the mechanisms all converge on a common pathway, serotonin.