Rhonda Patrick· PhD
Depression induced by injecting pro-inflammatory cytokine into blood can be reversed by supplementation with omega-3.
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Depression induced by injecting pro-inflammatory cytokine into blood can be reversed by supplementation with omega-3.
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person personally what I think is important is I think that because EPA is more of the anti-inflammatory it's involved in preventing the prostag gland in production and inflammation plays a major role in depression and we know this U because of several Studies have shown even injecting people with uh a pro-inflammatory cyto like interferon they inject people with that and they immediately become depressed but if they co-administer EPA with that they don't get depressed
We know this because healthy individuals that are injected with either a pro-inflammatory cytoine interferon gamma or lipopolysaccharide which is a component of bacterial cell membranes that elicits an immune response begin to experience depressive symptoms that can actually be alleviated with a polyunsaturated fatty acid icosapentinoic acid also known as EPA which is an omega-3 fatty acid that is well known for its anti-inflammatory properties.
those people that were injected with the pro-inflammatory cyto kind but were also given the omega-3 fatty acid known as iosa pentenoic acid or EPA that I have talked about quite a bit for a variety of reasons and also is renowned for its anti-inflammatory properties did not experience depress symptoms
What I'm getting at here is that, you know, it seems as though that study itself...and there's actually is more than one that showed this. You could cause or induce depressive symptoms in healthy individuals just by causing inflammation. And you could prevent that by giving someone "something that's anti-inflammatory."
I like to get both, but really uh depression is interestingly um EPA because of the anti-inflammatory effect as well.