Rhonda Patrick· PhD
A new meta-analysis of 17 studies found that people with the highest blood levels of omega-3 (EPA + DHA) had a 15-18% lower all-cause mortality than those with the lowest levels.
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The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
A new meta-analysis of 17 studies found that people with the highest blood levels of omega-3 (EPA + DHA) had a 15-18% lower all-cause mortality than those with the lowest levels.
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so so i you very recently published a study that correlated the omega-3 index to [Music] cause mortality is able to even predict uh mortality very very interesting study um i shared it on social media but i would love to talk about it yeah yeah sure that was a it's gonna be probably one of my capstone studies i think in in hindsight um it was a collaboration among 17 different cohorts like like the framingham studies of cohort women's health initiatives mesa epic these are all and from all around the world these are groups that have been recruited at one point in time blood samples taken fatty acid levels measured in that blood and then the investigators just follow this group of people over time to see what happens what kind of diseases they get you know who gets who dies who doesn't and so we had 17 of those pooled together and around 40 45 000 people all together where we had omega-3 levels at the beginning and then roughly um the total follow-up time when you're when you're looking at risk for death all cause mortality you obviously look in a given window of time because if you wait long enough it's one hundred percent everybody dies so you can't wait forever you gotta wait so so we we looked uh basically between age 65 and 75. who who died in that window of time and we found that the people had the highest omega-3 levels compared to the lowest were 15 or so less likely to die over that time and it was a very when you look at quintiles of omega-3 it was very dose dependent the
and those people were really half as likely to die as people who had but yeah and it was 0.07 p value so it wasn't statistically significant by standard metrics but in the race to understand what we can do about cobit we'll put up with a slightly non-significant strong trend in the right direction with good biology behind it to explain it
we found that the people had the highest omega-3 levels compared to the lowest were 15 or so less likely to die over that time and it was a very when you look at quintiles of omega-3 it was very dose dependent the higher the omega-3 the lower the risk and that was for total mortality