Andrew Huberman· PhD
It's known that omega-3, actually specifically EPA, is able to help serotonin. Inflammation inhibits the release of serotonin, and so EPA is actually able to blunt inflammatory responses along with DHA as well.
Loading…
The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
It's known that omega-3, actually specifically EPA, is able to help serotonin. Inflammation inhibits the release of serotonin, and so EPA is actually able to blunt inflammatory responses along with DHA as well.
Every Sunday: the week’s new conflicts and verdict changes — and nothing else.
Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
It's known that omega-3 actually specifically EPA is able to help serotonin in inflammation inhibits the release of serotonin. And so EPA is actually able to blunt inflammatory responses along with DHA as well.
EPA increases 5HT release from pre-synaptic neuron
I published a paper last year explaining how omega-3 increases serotonin system, which affects aggression/social behavior.
I think need higher dose of EPA since it regulates serotonin release
in addition to vitamin D omega-3 the Marine omega-3 fatty acids also regulate serotonin function so tryptophan gets converted into serotonin by the enzyme tph2 which is What vitamin D regulates but in the neuron in the presynaptic neuron serotonin has to be released into the synapse and the release of of Serotonin into the synapse depends on inflammation so when inflammation is High um whether that's because you're not eating a good diet you have gut issues you know whatever the cause many different things cause inflammation overactive immune you know system not getting the right micronutrients this causes the production of something called the E2 series prostaglandins E2 series prostaglandins have been shown if you're making them in the gut they cross over the blood brain barrier they get into the brain and they prevent the release of Serotonin so serotonin cannot be released from the pr synaptic synapse um or neuron into the synapse when inflammation's high well icosapent enoic acid the Marine fatty acid EPA stops the production of E2 series prostaglandins and because it dampens that production of E2 series progins it allows serotonin to be released from the presynaptic neuron
and how omega-3 fatty acids specifically the Marine omega-3 fatty acids icosapent anuic acid EPA and doah hexenoic acid DHA also regulate the serotonin system and how this is relevant for brain function and brain dysfunction
So there have been studies also showing that EPA and DHA are important for dopamine, serotonin. you know, when you have high inflammation, it stops the release of serotonin. You're not able to release serotonin from the from the preynapse.
So there have been studies also showing that EPA and DHA are important for dopamine, serotonin. you know, when you have high inflammation, it stops the release of serotonin. You're not able to release serotonin from the preynapse.