Achieving a high omega-3 index, associated with a 50% reduction in Alzheimer's risk, requires approximately two grams of omega-3 fatty acids per day.

“Usually, it's around two grams a day to get you from low to high.”

“An omega-3 index of 8% is the target - that means approximately 2 grams per day for most people.”

“People with a high omega-3 index (~10%) have about a 50% lower risk of Alzheimer’s disease compared with those at the low end (~4%).”

“Practically, it may take roughly 2 g/day of omega-3s to move from a low omega-3 index toward that higher, more protective range.”

“Aim for an omega-3 index ≥8% via ~1.5–2 g/day EPA+DHA (or high seafood).”

“And when we're talking about going from a low omega-3 index to a high omega-3 index, we're not talking about a lot. 1.5 to two grams of a high quality fish oil supplement is easy to do.”

“And so again, what Bill found is that individuals that had a high omega-3 index had about a 50% reduced risk of Alzheimer's disease compared to people with a low omega-3 index.”

“If they supplement, it seems as though if they're taking a triglyceride form, a little bit, maybe 1.5 to two grams a day. Um, I like to say two grams a day is really to be safe, but um, two grams a day of omega-3 fatty acids seem to get people from a low to a high omega-3, you know, index level.”

“So that's probably why when you get up to that high omega-3 index, which we'll talk about, it takes about two grams a day to get to that high omega-3 index.”