Mice engineered to lack the MFSD2A transporter had 60% less DHA in their brains compared to control mice, while DHA levels in the heart and liver remained unchanged.

“so the mfsd2a transporter that I've been referring to is specific to DHA and DHA the form of DHA is lysophosphatidylcholine DHA and that you know so that that specific we make it and so we basically get when we take in DHA from fish or from a supplement uh our bodies the higher amount of DHA that we take in we add that lysophosphatidylcholine group to the DHA”

“those Transporters of Omega-3 that are right at the same site you know of where you lose those parasites which is also really interesting and again there's a lot of animal evidence that suggests the role of that transporter in blood-brain barrier Integrity also again you can kind of like Connect the Dots here where you think okay well this is a DHA specifically a d it's DHA and phospholipid form transporter so it's like okay there's got to be something here with the omega-3”

“the mfsd2a transporter that I've been referring to is specific to DHA and DHA the form of DHA is isof phosph tial choline DHA”

“um what's really interesting that is that animal studies when you disrupt that transporter it causes like 50% you know breakdown of the bloodb brain barrier and like like greater than 50% loss of Omega-3 in the brain”

“inhibiting the transport of DHA into the brain (via Mfsd2a) totally breaks down the BBB.”

“Mice that were engineered to lack this transporter had sixty percent less DHA in their brain compared to controlled mice this was only specific to the brain as DHA levels in the heart and in the liver were the same as in controlled -”

“as we age and with dementia mfsd2a so the receptor for omega-3 is reduced at the blood vessels and there is also a link that where there is a reduction on this mfsd2a on blood vessels that's where we see parasite loss”