Paul Saladino· MD
Yes. Yeah. >> which is when you don't have enough of these things and you you hinted at this like when we we exist as humans by stripping electrons from the food we eat moving them through the cytoplasm into the mitochondria using intermediates FADH2 NADH to put these into the electron transport chain and then eventually creating molecular water and producing super oxide in in the mitochondria which is an important signal. Like you know there are valuable valuable oxidative species in the human body that we don't want to get rid of. It it it's amazing you say that to because like you when you produce super oxide it actually has unique signaling effects and then it goes to superoxid mutase to create you know things like uh well it there's a number of things that happen but they can then create hydro peroxide which then has signaling effects and then there's a specific aquaporin channel for hydro peroxide to go to transverse and then it go gets uh you know use like catalase or glutathion peroxide or something to be converted to water. So to your point, every free radical that's produced by the body, not everyone, but but there's a reason that your body has conserved a mechanism to produce these free radicals, >> they're valuable. >> They're very val it's it's a horic stress, right? This this process of hormesis where a small amount of a toxin can end up being beneficial for you. And when we exercise, we create free radicals. We're breathing a lot more oxygen. Obviously, we're going to we create more inflammation, but that stress is what mediates these benefits. So by taking high doses of conventional antioxidants, we're basically attenuating that very signal that we want.