Reactive oxygen and nitrogen species can damage cell membrane fluidity, making them more rigid and impairing the function of embedded proteins, transporters, and receptors.

“now lastly these reactive oxygen or reactive nitrogen species have also been shown to damage the lipid bilayer of your cell membranes now all the cells in your body including your neurons contain a cell membrane and these cell membranes have a certain fluidity to them and this reactive oxygen and nitrogen species can damage that fluidity and make them more rigid”