Andrew Huberman· PhD
so THC going back to kind of the pharmacology of this so THC if you look at how it interacts with the receptor um it's not it's not a heavy duty molecule so I mean this was kind of one of the things that came up before as well is this idea that th use a sledgehammer and it overrides endoc canabo by the way um Matt's referring to the fact that I said that in a previous solo episode about this um and there I was nesting it in the concentrations of THC that can be found in high THC cannabis yeah um so essentially what I was saying is that at very high THC concentrations the amount maybe not The Binding Affinity but the amount of THC that is available to the CB1 receptors is going to exceed what's normally found in terms of the amount of anandamide that can bind to CB1 receptors