Immediate-release amphetamines can cause withdrawal symptoms like energy crashes and mood deterioration.

“most people not all but most experience some withdrawal as it's going off and although when we're using this for ADHD we focus on the cognitive executive function benefits the focus the attention the concentration and people can experience that many people who weren't even aware of it increasing their energy feel my energy crashing as I go off of it or many people who wen't aware that it was actually elevating mood to any extent feel oh my God I'm crashing and I'm crying and cranking and miserable now”