Oral Minoxidil dosage should start at 0.25mg and increase as needed to avoid side effects.

“I would hope that if people are working with a physician or if they're not in taking Minoxidil, that they would start with the lowest possible dose. For oral Minoxidil, that would be 0.25 milligrams and then increase it as needed rather than jumping in right at five milligrams because some of those side effects, in particular the fluid retention and the hyper prolactinemia can be pretty uncomfortable and can disrupt a lot of aspects of life that most all of us consider desirable.”