MDMA may be potentially neurotoxic and should not be taken more often than every three months due to concerns for serotonergic toxicities. — Whalespan
MDMA may be potentially neurotoxic and should not be taken more often than every three months due to concerns for serotonergic toxicities.
⚠ High risk
We can't find evidence that holds up here. Proponents are reasoning from mechanism or analogy rather than direct human data, and the most credible skeptics raise objections we can't dismiss.
✕NOTSUPPORTED
⚠
High-risk intervention — consult a physician before acting.Drug-drug interactions, dose-dependence, and screening contraindications apply.
“and yet there is still the risk of neurotoxicity if people are taking high doses of MDMA or taking it very frequently or certainly if they are taking it in conjunction with other drugs or or I should say and or taking MDMA in settings that can promote neurotoxicity”
“I remain somewhat concerned that it is potentially neurotoxic I wouldn't want to take too much of it I haven't taken it for years and I have much less of a concern for other psychedelics I think LSD is I mean there's there's no evidence that it's neurotoxic for instance having spoken with people psychiatrists who have taken care of patients who have probably taken too much MDMA the two things that I have learned from them which echo what you're saying is yeah it's generally safe but it's very important like any drug I mean these aren't regulated compounds right so right you're always running a risk when you take these things of other things that the drug is cut with and there's no activity that can be amplified as a result of that and the second thing that I've been told is anything over a frequency of about every three months and you start to run a risk of these serotonergic toxicities down the line”