Increased serotonin from SSRIs can be taken up by dopamine synapses, potentially reducing the rewarding properties of dopamine.

“who explained that the increased serotonin from SSRIs can be taken up by dopamine synapses and can reduce the rewarding properties of dopamine.”

“But you know, if you were a system and you thought that the positive juice was dopamine and the negative juice was serotonin and you put the negative juice in the positive terminals, then the cells that control the release of that are going to chatter for positive things. You might start negatively conditioning on things that you should actually pursue and learn about.”