The evidence is convergent. Multiple independent sources reach the same conclusion, the underlying mechanism is well-characterized, and even the field's most cautious voices treat it as worth doing.
Nicotine triggers the release of dopamine from the nucleus accumbens. This is what gives nicotine its rewarding properties. It increases motivation. It tends to give a not so subtle, but very transient increase in feelings of wellbeing and alertness and motivation.
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Native comments, Twitter mentions, and Reddit threads about this claim — surfaced together so the conversation isn't fragmented across platforms.
Bookmarking — the dossier-vs-overview split is the right call. Most of the time I want overview; sometimes I want receipts.
Would love a "what would change this verdict" RSS feed. Sign me up if it exists.
nicotine increases dopamine and that's why it feels so good, it makes you want more of it
This is what makes the rewarding properties or sometimes referred to as the reinforcing properties of nicotine so powerful. This is why so many billions of people ingest nicotine in one form or another. It's also why nicotine is so hard to quit because there's a potent increase in dopamine from multiple neural circuit pathways within this mesolimbic reward circuitry.
nicotine both increases dopamine, but also decreases the activity of GABA. And so this is like pushing on the accelerator for dopamine, but also removing the brake.
the mesolympic reward pathway that releases dopamine and typically when nicotine is increased in our system dopamine goes up that's one of the reasons why nicotine is reinforcing we like it it's a we seek it out
when nicotine is increased in our system dopamine goes up that's one of the reasons why nicotine is reinforcing we just like it it's a we seek it out